PTH-rP related peptide cancer therapeutics
AssigneePevion Biotech Ltd.
InventorsPierpaolo Correale, Maria Cusi, Guido Francini
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Abstract
Compositions comprising PTH-rP peptides, combinations thereof, and multiepitope PTH-rP peptides, vectors for their delivery to antigen presenting cells, as well as methods are provided which are useful in the immunotherapy of parathyroid hormone related peptide expressing malignancies.
Claims28
An isolated immunostimulatory PTH-rP peptide comprising a fragment of the amino acid sequence of SEQ ID NO:1 or a functional variant thereof comprising one or more amino acid additions, substitutions or deletions.
A multiepitope peptide comprising two or more PTH-rP peptides.
A virosome comprising the expression vector of 11.
A composition comprising a virosome encapsulating a nucleic acid comprising SEQ ID NO:9.
Dependencies are inferred from the claim text.