Decontamination of prion-contaminated surfaces with phenols
AssigneeSTERIS Inc.
InventorsGerald McDonnell, Herbert Kaiser, Kathleen Antloga, Shahin Keller
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Abstract
A method of decontaminating a surface or liquid which is contaminated with prions includes treating the surface with a composition which includes one or more phenol. Phenols which are particularly effective include p-chloro-m-xylanol, thymol, triclosan, 4-chloro, 3-methylphenol, pentachlorophenol, hexachlorophene, 2,2-methyl-bis(4-chlorophenol), and p-phenylphenol.
Claims20
A method of treating a body which is contaminated with prions, the method comprising:
- contacting the body with a composition comprising a phenol to inactivate prions on the body.
A method of determining the effectiveness of a phenol-based decontaminant composition on a material which is contaminated with prions comprising:
- combining a solution of the phenol-based decontaminant with a protein material;
- and
- determining a measure of the phenol taken up by the protein material;
- and
- determining the effectiveness of the composition based on the amount of phenol taken up.
Dependencies are inferred from the claim text.