Loading patent…
AssigneeNew York University
InventorsBenjamin Margolis, Joseph Schlessinger, Vijay Yajnik
Estimating the term…
The present invention concerns methods for diagnosis and treatment of diseases or disorders characterized by abnormal cellular signal transduction involving a newly identified region, herein termed the “APB domain.” APB domain binding between proteins is believed to play an important role in signal transduction pathways and, thereby, influence cellular events. Thus, APB mediated activity plays a role in signal transduction pathways and agents modulating APB mediated activity can be used to treat diseases or disorders involving proteins containing APB domains.
1-12. (Canceled)
A method of assaying for agents useful for disrupting APB interactions or in the diagnosis of APB diseases or disorders, comprising the step of measuring the ability of an agent to bind to an APB recognition region or an APB domain.
16-18. (Canceled)
A method of identifying an agent able to bind to an APB domain or an APB recognition region, comprising:
A method of identifying an agent able to promote APB binding complexes, comprising:
A method of identifying an agent able to promote APB binding complexes, comprising:
Dependencies are inferred from the claim text.