Products containing quantum of bioparticles and method for production thereof

A process for forming a product containing a defined small number of microorganisms, the process comprising:

• providing microorganisms selected from the group consisting of viruses, bacteria, yeast, fungi, parasites, protozoa, cells and mixtures thereof in suspension;
• selecting a defined number of the microorganisms of between 1 and 1000 from the suspension by means to sense a microorganism;
• capturing the defined number of microorganisms in a frozen body;
• and
• drying the frozen body to produce a product containing the defined number of microorganisms, wherein the product is capable of being transferred between containers in its solid form without substantial loss of the microorganisms, wherein the product is capable of releasing the microorganisms in a liquid, and wherein the defined number of the microorganisms in the product when measured in two or more replicates is within a standard deviation of 10% or less of the defined number.

A process for forming a solid product containing a defined small number of a viable bacteria, the process comprising:

• providing bacteria in suspension;
• selecting a defined number of the bacteria of between 5 and 100 in a drop using a flow cytometer to sense a bacterium;
• adding the drop containing the bacteria to liquid nitrogen to form a frozen ball containing the defined number of the bacteria;
• and
• subjecting the frozen ball to freeze-drying to form a substantially dry solid product containing the defined number of the bacteria, wherein the product is capable of being transferred between containers in its solid form without loss of the bacteria, and wherein the product is capable of releasing the defined number of viable bacteria in a liquid, and wherein the defined number of the bacteria in the product when measured in two or more replicates is within a standard deviation of less than about 5% of the desired number of bacteria.