Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family
AssigneeDegussa AG
InventorsMechthild Rieping, Nicole Siebelt
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Abstract
A process for the fermentive preparation of an L-amino acid, in particular L-threonine, comprising: a) fermentation of a microorganism of the Enterobacteriaceae family which produces the desired L-amino acid and in which the rseB gene or nucleotide sequences which code for it is enhanced, in particular, over-expressed, b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and c) isolation or recovery of the desired L-amino acid.
Claims20
A process for the preparation of an L-amino acid comprising:
- fermenting a suitable substrate or culture medium with a microorganism of the Enterobacteriaceae family, which comprises an enhanced or overexpressed rseB gene or rseB gene variant, under conditions which are suitable for the expression of the rseB gene or suitable for formation of an rseB gene product, and
- isolating or recovering the L-amino acid.
A recombinant microorganism of the Enterobacteriaceae family in which the rseB gene, rseB gene variant, or nucleotide sequences which code for the rseB gene product are present in over-expressed form.
Dependencies are inferred from the claim text.