Methods and compositions for the treatment and prevention of Staphylococcus and other bacterial infections
OwnerNaomi Balabaninventor
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Abstract
The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria, including in particular bacteria in which a RAP-type and/or TRAP-type molecule plays a role in pathogenesis. This includes Staphylococcus species.
Claims14
A method of preventing or treating an infection caused by any bacterial infection caused by any bacteria species in which RAP plays a role in pathogenesis, comprising:
- administering to a subject an amount of a RAP type polypeptide effective to elicit an antibody response in the subject to prevent or treat a bacterial infection caused by a bacteria species in which a RAP type molecule plays a role in pathogenesis.
A method of preventing or treating an infection caused by any bacterial infection caused by any bacteria species in which RAP plays a role in pathogenesis, comprising:
- administering to a subject having or at risk of a bacteria infection caused by a bacteria in which RAP type molecule plays a role in pathogenesis an amount of RIP or a RIP derivative effective to treat or prevent the bacterial infection.
A method of preventing or treating an infection caused by any bacterial infection caused by any bacteria species in which a TRAP type molecule plays a role in pathogenesis, comprising:
- administering to a subject an amount of a TRAP type polypeptide effective to elicit an antibody response in the subject to prevent or treat a bacterial infection caused by a bacteria species in which a TRAP type molecule plays a role in pathogenesis.
Dependencies are inferred from the claim text.