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US 2004/0072255 A1Published application
Isolated post-translationally modified mammalian proteins for monitoring and diagnosing muscle damage
AssigneeQueen's University at Kingston
InventorsJennifer E. Van Eyk, Jeremy A. C. Simpson, Ninetta Buscemi, Michelle K. Quick
Life of this patent
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Abstract
Isolated phosphorylated troponin I proteins useful in diagnosing and monitoring the phosphorylation state of injured muscle tissue are provided. Also provided are compounds, kits and methods for assessing the phosphorylation state of these troponin I proteins and modulating the phosphorylation state of these troponin I proteins in a subject.
Claims26
An isolated post-translationally modified myofilament protein comprising a troponin I protein phosphorylated at its C terminus or adjacent to its minimal inhibitory region.
Dependencies are inferred from the claim text.