Prolonged release microspheres for injectable administration
AssigneesMainelab, Laboratoires des Produits Ethiques Ethypharm
InventorsClaire Dulieu, Joel Richard, Jean-Pierre Benoit
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Abstract
The present invention provides microspheres intended to be administered by injection comprising a protein active ingredient and an agent coating the active ingredient intended to prolong its release, wherein they are free of any trace of organic solvent and they can be obtained according to a coating method involving bringing the active ingredient and the coating agent into contact, with stirring, in a supercritical fluid, said coating agent being soluble in this supercritical fluid.
Claims14
Microspheres intended to be administered by injection or by the subcutaneous or intramuscular route comprising a protein active ingredient and an agent coating the active ingredient intended to prolong its release, wherein they are free of any trace of organic solvent and they can be obtained according to a coating method involving bringing the active ingredient and the coating agent into contact, with stirring, in a supercritical fluid, said coating agent being soluble in this supercritical fluid.
Dependencies are inferred from the claim text.