Preventive or therapeutic agent for inflammatory bowel disease comprising IL-6 antagonist as an active ingredient
AssigneeChugai Seiyaku Kabushiki Kaisha
InventorsHiroaki Ito, Mitsunari Yamamoto, Tadamitsu Kishimoto
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Abstract
A preventive or therapeutic agent for inflammatory bowel disease such as Crohn's disease and ulcerative colitis said agent comprising as an active ingredient an interleukin-6 (IL-6) antagonist such as an antibody directed against IL-6 receptor.
Claims39
A preventive or therapeutic agent for inflammatory bowel disease comprising an interleukin-6 (IL-6) antagonist as an active ingredient.
An agent for suppressing weight loss in inflammatory bowel disease said agent comprising an IL-6 antagonist as an active ingredient.
An agent for suppressing weight loss in inflammatory bowel disease said agent comprising an antibody against IL-6 receptor as an active ingredient.
A method of preventing or treating inflammatory bowel disease which method comprises administering an interleukin-6 (IL-6) antagonist to the subject.
The method according to claim 0.22 wherein the humanized antibody against IL-6 receptor is a humanized PM-1 antibody.
A method of suppressing weight loss in inflammatory bowel disease which method comprises administering an IL-6 antagonist to the subject.
A method of suppressing weight loss in inflammatory bowel disease which method comprises administering an antibody against IL-6 receptor to the subject.
The use of an interleukin-6 (IL-6) antagonist for the production of a preventive or therapeutic agent for inflammatory bowel disease.
The use of an IL-6 antagonist for the production of an agent for suppressing weight loss in inflammatory bowel disease.
The use of antibody directed against IL-6 receptor for the production of an agent for suppressing weight loss in inflammatory bowel disease.
Dependencies are inferred from the claim text.