Use of galectin-3 and galectin-7 to promote the re-epithelialization of wounds
AssigneeTrustees of Tufts College
InventorsNoorjahan Panjwani, Zhiyi Cao
Life of this patent
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Abstract
Methods for the therapeutic treatment of epithelial wounds in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-3 protein and/or a galectin-7 protein are provided. Pharmaceutical compositions comprising a pharmaceutically suitable carrier or diluent and as an active agent a galectin-3 protein and/or a galectin-7 protein are also provided.
Claims38
A method for the therapeutic treatment of epithelial wounds in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-3 protein.
A method for the therapeutic treatment of epithelial wounds in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-7 protein.
A pharmaceutical composition having a promoting effect on the re-epithelialization of a wound, said composition comprising a pharmaceutically suitable carrier or diluent and an amount of a galectin-3 protein sufficient to promote the re-epithelialization of said wound.
A pharmaceutical composition having a promoting effect on the re-epithelialization of a wound, said composition comprising a pharmaceutically suitable carrier or diluent and an amount of a galectin-7 protein sufficient to promote the re-epithelialization of said wound.
A method for the therapeutic treatment of epithelial wounds in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a substance that influences the expression of epithelial cell surface receptors or receptors of the extracellular matrix.
A method for the therapeutic treatment of epithelial wounds in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a substance that influences the expression of a galectin-7 protein.
Dependencies are inferred from the claim text.