Compositions with enhanced antimicrobial efficacy against acanthamoebae
AssigneeBausch & Lomb Incorporated
InventorsRoya Borazjani, Erning Xia, Daniel M. Ammon JR., Joseph C. Salamone, Zhenze Hu, Alyce K. Dobie
Life of this patent
Estimating the term…
Abstract
Ophthalmic compositions such as eye drop and contact lens treating solutions include a polycationic material to enhance antimicrobial efficacy against protozoans such as acanthamoebae. One preferred class of polycationic materials is cationic cellulose derivatives.
Claims18
A method for enhancing antimicrobial efficacy of a composition against acanthamoebae comprising including a polycation material in said composition.
An ophthalmic composition comprising a primary antimicrobial agent, and a polycation material in an aqueous solution, wherein said polycation material enhances the antimicrobial efficacy of the primary antimicrobial agent.
The ophthalmic composition according to 10, wherein the polycation material includes a cationic cellulose material.
A method for enhancing antimicrobial efficacy of a contact lens against acanthamoebae, comprising contacting said contact lens with a solution comprising a primary antimicrobial agent and a polycation material.
A method for enhancing antimicrobial efficacy of an ophthalmic composition against acanthamoebae, comprising including in said composition a cationic cellulose material.
An ophthalmic composition comprising a primary antimicrobial agent and a polycation material that enhances the antimicrobial efficacy of said primary antimicrobial agent, wherein said composition has enhanced efficacy against acanthamoebae than a similar composition lacking the polycation material.
Dependencies are inferred from the claim text.