Programmable scaffold and method for making and using the same

Abstract

A programmable scaffold which is a three-dimensional scaffold having interconnected pore structures and biologically active molecules physically entrapped therein. Preferably, the scaffold is a lyophilized hydrogel of crosslinked alginate or hyaluronic acid. The scaffold can be arrayed on a platform and loaded with various combinations of biologically active molecules for high throughput and high parallel screening and tissue engineering. A method for making and modifying the scaffold having steps of impregnating the scaffold with solutions of biologically active molecule and lyophilizing the impregnated scaffold.

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