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US 2004/0062824 A1Published application
Composition for treating chronic venous insufficiencies using an extract of red vine leaves
AssigneeBoehringer Ingelheim International GmbH
InventorsAnke Esperester, Hans W. Frey, Jean-Michel Vix
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Abstract
The invention relates to a dietary supplement consisting of an aqueous extract of red vine leaves and an acceptable carrier which prevents and reduces the discomfort relating to mild-to-moderate chronic venous insufficiency of the legs.
Claims8
An improved composition in a form suitable for oral administration consisting of an active principle, and a pharmaceutically, cosmetically or dietetically acceptable carrier, the improvement wherein is that said active principle consists essentially of an aqueous extract of red vine leaves containing:
- 2 to 20% flavonoids and less than about 0.15% anthocyanins;
- wherein said aqueous extract of red vine leaves is obtainable by a method comprising the steps of:
- (a) collecting red vine leaves at a point of time when the content in flavonoids has reached an optimum;
- (b) drying and crushing the leaves;
- (c) cutting the leaves to pieces;
- (d) extracting the leaves with water at temperatures from 60 to 80° C. for 6 to 10 hours in an exhaustive percolation;
- and, optionally,
- (e) concentrating the obtained extract;
- and
- wherein the improved composition contains an amount of said aqueous extract of red vine leaves sufficient for administration in dosages corresponding to 350-750 mg daily.
7 more elements
Dependencies are inferred from the claim text.