Apparatus and method for monitoring characteristics of pharmaceutical compositions during preparation in a fluidized bed
OwnerStaffan Folestadinventor
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OwnerStaffan Folestadinventor
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The present invention relates to a method and apparatus for monitoring characteristics of a pharmaceutical composition during preparation thereof by in the process vessel (1) of a fluidized bed apparatus, wherein a measuring device (11, 11′) performs a spectometric measurement on the pharmaceutical composition in a wetting zone (B) into which a processing fluid is injected. The method also comprises the generic use of an optical probe device in spectrometric measurements, the probe device being capable of transmitting a two-dimensional image of radiation emitted from a monitoring area in the process vessel (1).
Fluidized bed apparatus for preparation of a pharmaceutical composition by a particle-forming process, wherein said apparatus defines a wetting zone (B) into which a processing fluid is injected, and a drying zone in which the processing fluid is at least partly solidified, characterized by a measuring device (11, 11′) which is arranged to perform a spectrometric measurement on the pharmaceutical composition in the wetting zone (B), to thereby monitor characteristics of said pharmaceutical composition during preparation thereof.
A method for monitoring characteristics of a pharmaceutical composition during preparation thereof by a particle-forming process in a fluidized bed apparatus, wherein said fluidized bed apparatus defines a wetting zone (B) into which a processing fluid is injected, and a drying zone in which the processing fluid is at least partly solidified, characterized by the step of performing a spectrometric measurement on the pharmaceutical composition in the wetting zone (B).
A method of monitoring physical and/or chemical properties of a pharmaceutical composition during preparation thereof in a process vessel (1), said method comprising the steps of:
Dependencies are inferred from the claim text.