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US 2004/0053834 A1Published application
Enzymes involved in glycoprotein and glycolipid metabolism
OwnerPreeti G Lal, Henry Yue +5inventors
InventorsPreeti G Lal, Henry Yue, Dyung Aina M. Lu, Ameena R. Gandhi, Kavitha Thangavelu, Narinder K. Chawla, Mariah R. Baughn
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Abstract
The invention provides human enzymes involved in glycoprotein and glycolipid metabolism (GLYCOS) and polynucleotides which identify and encode GLYCOS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorder associated with aberrant expression of GLYCOS.
Claims59
An isolated polypeptide selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-2,
- b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-2,
- c) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-2, and
- d) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-2.
1 more element
An isolated polynucleotide selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence selected from the group consisting of SEQ ID NO:3-4,
- b) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to a polynucleotide sequence selected from the group consisting of SEQ ID NO:3-4,
- c) a polynucleotide complementary to a polynucleotide of a),
- d) a polynucleotide complementary to a polynucleotide of b), and
- e) an RNA equivalent of a)-d).
2 more elements
Dependencies are inferred from the claim text.