US 2004/0024183 A1Published application

Transporters and ion channels

OwnerErnestine A Lee, Henry Yue +24inventors

InventorsErnestine A Lee, Henry Yue, Preeti G. Lal, Narinder K Chawla, Mariah R Baughn, Bridget A Warren, Sally Lee, Madhusudan M Sanjanwala, Monique G Yao, Jayalaxmi Ramkumar, Michael B Thornton, Ameena R Gandhi, Jennifer L Policky, Vicki S Elliott, Brigitte E Raumann, Chandra S Arvizu, Christopher M Bruns, Amir Naini, April J A Hafalia, Danniel B Nguyen, Yuming Xu, Dyung Aina M Lu, Craig H Ison, Jennifer A Griffin, Roopa M Reddy, Neil Burford

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Abstract

The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

Claims107

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-26,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-26,
c) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-26, and
d) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-26.

1 more element

Dependencies are inferred from the claim text.