Synergistic antioxidant combination of delta tocols and polyphenols
AssigneeNestec S.A.
InventorsNathalie Hasler-Nguyen, Jacob Zijlstra, John P. Troup
Life of this patent
Estimating the term…
Abstract
A source of δ-tocotrienol and/or-tocopherol acts synergistically with an antioxidant source comprising polyphenols, to effect suppression of LDL oxidation in serum. The combination of these two antioxidant sources has wide-ranging applications in treatment of medical conditions arising from free radical generation, including arteriosclerosis and cancer.
Claims24
A composition comprising a mixture of
- (a) a source of δ-tocol comprising greater than 2% by weight δ-tocol;
- and
- (b) polyphenols,
- with the proviso that when (b) comprises citrus flavonoids, (a) comprises δ-tocopherol.
A composition comprising in a daily dosage:
- (a) at least 5 mg δ-tocopherol or of a mixture of δ-tocotrienol and δ-tocopherol;
- and
- (b) polyphenols.
A composition comprising in a daily dosage:
- (a) at least 5 mg of δ-tocotrienol;
- and
- (b) polyphenols other than citrus flavonoids.
A composition according to any preceding claim wherein the dry weight ratio of (b):(a) is ≧1, preferably ≧3.
A composition according to any preceding claim which comprises one or more flavonoids.
A composition according to any preceding claim wherein the weight ratio of δ-tocol to α-tocopherol is greater than 0.65.
A composition according to any preceding claim wherein the source of component (a) is a Tocotrienol Rich Fraction (TRF) from palm oil or rice bran oil or a blend of tocopherols, and the source of polyphenols (b) comprises green tea or Pu Erh tea or extracts or mixtures thereof.
A composition according to any preceding claim which comprises a single polyphenolic antioxidant source.
A food or beverage product comprising
- (a) a source of δ-tocol comprising greater than 2% by weight δ-tocol;
- and
- (b) an antioxidant source comprising polyphenols,
- and optionally one or more of carbohydrate, fat, fibre and protein.
Use of a composition comprising
- (a) a source of δ-tocol preferably comprising greater than 2% by weight δ-tocol;
- and
- (b) an antioxidant source comprising polyphenols,
- as a preservative for preventing spoilage of food and beverage products.
A kit comprising:
- (a) a source of δ-tocol preferably comprising greater than 2% by weight δ-tocol;
- and
- (b) an antioxidant source comprising polyphenols,
- for separate, sequential or simultaneous administration.
A cosmetic composition comprising:
- (a) a source of δ-tocol preferably comprising greater than 2% by weight δ-tocol;
- and
- (b) an antioxidant source comprising polyphenols;
- and
- (c) a cosmetic base.
Dependencies are inferred from the claim text.