Cholesterol-lowering agent
OwnerHassan Hajjaj, Catherine Mace +2inventors
InventorsHassan Hajjaj, Catherine Mace, Peter Niederberger, Laurent-Bernard Fay
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Abstract
A hypocholesterolaemic agent and a process for its preparation by extraction from edible fungi, along with methods of use of the agent for preventing the synthesis of cholesterol in a person. These methods include the administration of the agent alone or in a food or beverage. The foods or beverages that contain this agent are another feature of the invention.
Claims13
A process for preparing a hypocholesterolaemic agent which comprises:
- steeping an edible fungus in a first solvent under temperature and time conditions effective to extract an active fraction in a liquid phase,
- separating the liquid phase from solid materials,
- obtaining a dry extract of the active fraction from the liquid phase,
- forming an aqueous phase of the dry extract and water,
- contacting the aqueous phase with a second solvent that has a lower polarity than the first solvent and that is immiscible with water, with the contacting conducted under conditions sufficient to extract the active fraction in an organic phase,
- separating the organic phase from the aqueous phase, and
- obtaining as the hypocholesterolaemic agent the active fraction recovered from the organic phase.
An edible composition for inhibiting synthesis of cholesterol in a person comprising a food or beverage and the hypocholesterolaemic agent of claim 11 in an effective amount therein.
Dependencies are inferred from the claim text.