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AssigneePharmaceutical Discovery Corporation
InventorsSolomon S. Steiner, Cohava Gelber, Robert S. Feldstein, Roderike Pohl
Estimating the term…
Compositions containing biologically active molecules encapsulated in self-assembling, diketopiperazine microspheres (TECHNOSPHEREs™) and methods for making and administering such compositions are described herein. The compositions can be used to immunize individuals against agents of biological warfare. The biologically active molecules include atropine, antibodies, antigens, and antibiotics. The compositions can be placed in an inhalation device for self-administration. Pulmonary delivery of TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics provides an accelerated onset of immunity to the targeted disease. Furthermore, the TECHNOSPHERE™ encapsulated atropine, antibodies, vaccines, and antibiotics are stable formulations, suitable for stockpiling, rapid dissemination and mass treatment.
A pulmonary formulation comprising
A method of treating a person comprising administering to the person a pulmonary formulation comprising
A device for use in treating or preventing an individual exposed to a biological weapon, wherein the device contains diketopiperazines particles comprising an effective amount of a biologically active agent to prevent or treat the individual exposed to a biological weapon, and means for introducing the diketopiperazine particles into the pulmonary system of the individual.
Dependencies are inferred from the claim text.