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AssigneeSankyo Company, Limited
InventorsTsuneki Ohsawa, Ikuo Takagi, Ippei Shimizu, Tatsuhito Kondo, Masato Nakayama, Yasuhiro Torizumi
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Compositions having excellent blood lipid peroxide lowering activity are provided. In particular, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at least one substance selected from the group consisting of taurine, pantethine and inositol hexanicotinate. Use of these compositions enables the provision of excellent preventive or remedial agents capable of lowering the concentration of lipid peroxides in the blood which show effects of injuring vascular endothelial cells, accelerating platelet aggregation, forming foam cells, etc.
A pharmaceutical composition for lowering lipid peroxides in the blood, said composition comprising a pharmaceutically acceptable additive agent in admixture with pravastatin or its pharmaceutically acceptable salt and one or more compounds selected from the group (a) consisting of taurine, pantethine and inositol hexanicotinate, together with a pharmaceutically acceptable carrier or diluent.
A kit comprising a plurality of separate containers, wherein at least one container contains pravastatin and at least one different container contains one or more compounds selected from the group (a) consisting of taurine, pantethine and inositol hexanicotinate, the administered combination being suitable for lowering blood lipid peroxide levels in a human.
A method of lowering blood lipid peroxide levels in a human, comprising administering to a human in need thereof an effective amount of an agent comprising pravastatin in combination with one or more compounds selected from the group (a) consisting of taurine, pantethine and inositol hexanicotinate.
Dependencies are inferred from the claim text.