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US 2003/0228295 A1Published application
Use of human neural stem cells secreting GDNF for treatment of parkinson's and other neurodegenerative diseases
OwnerClive N. Svendseninventor
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Abstract
A method of treating brain disorders involving loss of cells that respond to GDNF is disclosed. In one embodiment, the invention comprises the steps of (a) transducing human neural stem cells with glial-derived neurotrophic factor (GDNF), wherein the GDNF gene is under control of an inducible promoter system, and (b) transplanting the transduced cells into the brain of a patient.
Claims17
A method of treating brain disorders involving loss of cells that respond to GDNF comprising the steps of
- (a) transducing human neural stem cells with glial-derived neurotrophic factor (GDNF), wherein the GDNF gene is under control of an inducible promoter system, and
- (b) transplanting the transduced cells into the brain of a patient, wherein GDNF is expressed.
Dependencies are inferred from the claim text.