Systems and methods for monitoring health and delivering drugs transdermally

A microfabricated device for sampling analytes from the skin of a subject, comprising:

• a detection chamber for receiving analytes retrieved from the skin of a subject;
• a patch which changes color when contacted by predetermined analytes, located attached to said microfabricated device in association with said detection chamber;
• and
• detectors associated with said detection chamber, for detecting a change of color of the patch indicating the presence of a predetermined analyte.

A transdermal sampling system, comprising:

• a microfluidic assembly for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject;
• at least one detector system for identifying and quantifying said at least one analyte;
• and
• at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector.

A transdermal sampling system, comprising:

• a microfluidic assembly for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject;
• at least one detector system for identifying and quantifying said at least one analyte;
• and
• at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector,
• wherein the microfluidic assembly contains a physiologically compatible fluid for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject, and
• wherein the microfluidic assembly is adhered to the skin of the subject.

A transdermal sampling system, comprising:

• a microfluidic assembly for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject;
• at least one detector system for identifying and quantifying said at least one analyte;
• and
• at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector,
• wherein at least one surface of the microfluidic assembly is modified.