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US 2003/0224060 A1Published application
Polyester polyol nanocapsules, compositions thereof, and methods of use
AssigneeL'oreal
InventorsJean-Thierry Simonnet, Gilles Guerin
Life of this patent
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Abstract
The present invention relates generally to nanocapsules having a core-envelope structure where the core contains a lipophilic active agent and the envelope contains at least one polyester polyol obtained by polycondensation of an aliphatic dicarboxylic acid with at least two alkanediols or with at least one alkanediol and at least one hydroxyalkyl alkanediol. These nanocapsules make it possible to stabilize lipophilic active agents that are difficult to stabilize, especially retinol esters such as retinyl propionate.
Claims26
A nanocapsule having a core-envelope structure and comprising:
- a lipid core comprising at least one lipophilic active agent, and
- a water-insoluble polymer envelope comprising at least one polyester polyol having a weight-average molecular weight less than 5000 obtained by polycondensation of at least one aliphatic dicarboxylic acid with at least two alkanediols or with at least one alkanediol and at least one hydroxyalkyl alkanediol optionally comprising an alkyl chain.
Dependencies are inferred from the claim text.