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AssigneesTAITO CO. LTD, a Japanese corporation, JAPAN SCIENCE AND TECHNOLOGY CORPORATION, a Japanese corporation
InventorsKazuo Sakurai, Seiji Shinkai, Taro Kimura, Kengo Tabata, Kazuya Koumoto, Oliver Gronwald
Estimating the term…
Disclosed is a gene carrier composed of a hydrogen-bonding polymer having a polymer chain with hydrogen-bonding sites formed on the polymer chain, in which the polymer chain has a conformation similar to the conformation of a nucleic acid, and particularly, the polymer chain has helix parameters similar to the helix parameters of a nucleic acid of a helix structure. In a preferred embodiment, the hydrogen-bonding polymer is composed of β-1,3-glucan such as schizophyllan. The carrier can be expected to be applied as a vector and a separator for nucleic acids because it is capable of interacting with a nucleic acid to form a complex with the nucleic acid and thus carrying the nucleic acid.
A gene carrier capable of interacting with a nucleic acid to form a complex, wherein said gene carrier is composed of a hydrogen-bonding polymer having a polymer chain with hydrogen-bonding sites formed on the polymer chain, said polymer chain having a conformation similar to the conformation of the nucleic acid.
A gene carrier capable of interacting with a nucleic acid of a helix structure to form a complex, wherein said gene carrier is composed of a hydrogen-bonding polymer having a polymer chain with hydrogen-bonding sites formed on the polymer chain, said polymer chain having helix parameters similar to the helix parameters of the nucleic acid.
A nucleic acid-polymer complex composed of a nucleic acid and a hydrogen-bonding polymer having a polymer chain with hydrogen-bonding sites formed on the polymer chain, said polymer chain having helix parameters similar to the helix parameters of the nucleic acid, wherein the nucleic acid is bonded to the hydrogen-bonding polymer through the hydrogen-bonding sites.
Dependencies are inferred from the claim text.