Process for producing an implantable apparatus comprising a biomedical device coated with crosslinked TPU
OwnerAlan M. Zamoreinventor
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Abstract
A method for producing increased resistance to biodegradability is provided for biomedical devices subject to in vivo implantation. Among the steps required to produce such resistance are the application of a thermoplastic polyurethane coating to the device to provide a coating, and the subsequent crosslinking of the thermoplastic polyurethane coating through the application of radiation of a sufficient intensity and duration to convert said thermoplastic polyurethane coating to a thermoset coating possessing the attribute of increased biostability.
Claims17
A method for manufacturing a coated biomedical device exhibiting enhanced in vivo biostability comprising:
- (a) applying a radiation cross-linkable thermoplastic polyurethane coating to the device in order to insulate said device from biological elements;
- and
- (b) irradiating said thermoplastic polyurethane coating to form a thermoset coating through the application of radiation of a sufficient intensity and duration to cause said thermoplastic polyurethane coating to convert to a thermoset coating, said thermoset coating exhibiting enhanced in vivo biostability relative to said thermoplastic coating.
An apparatus for use in in vivo implantation comprising a biomedical device, at least a portion of which is encapsulated in a coating to provide an encapsulated device, said encapsulated device being encapsulated with a cross-linked thermoplastic polyurethane coating providing enhanced biostability as compared to a biomedical device free of crosslinked thermoplastic polyurethane coating.
Dependencies are inferred from the claim text.