US 2003/0211456 A1 · Method of profiling a plant extract

Abstract

The present invention is directed to a method of establishing an “identity” of Ginkgo biloba leaves or isolated ginkgolide B (GKB) or another component of the extract of Ginkgo biloba leaves, by obtaining a “gene regulation profile”. The invention is also directed to a method of verifying the identity of a Ginkgo biloba extract by comparing the gene regulation profile of a Gingko biloba extract of unknown or questionable origin with the gene regulation pofile of a Gingko biloba extract of known origin. The present invention is further directed to a method of establishing a gene expression profile of Ginkgolide A, Ginkgolide B or any other component isolated from a Ginkgo biloba extract, more particularly, from EGB 761®.

Claims8

Dependent claims

A method of establishing a gene regulation profile of a Gingko biloba extract or a component of the Ginkgo biloba extract, which comprises the steps of:

obtaining at least one batch of untreated cells;
treating a first batch of cells with an extract of Ginkgo biloba or a component of the Ginkgo biloba extract to obtain a treated batch of cells;
quantifying an affect on the expression of one or more genes of the treated cells to obtain a quantity of affected genes;
and
comparing the quantity of affected genes with a quantity of genes of cells not treated with Ginkgo biloba or a component of the Ginkgo biloba extract to obtain the gene regulation profile of the Ginkgo biloba extract or a component of the Ginkgo biloba extract.

2 more elements

Dependencies are inferred from the claim text.

Method of profiling a plant extract

Life of this patent

Method of profiling a plant extract

Life of this patent

Abstract

Claims8