Process for the biological production of l-pipecolic acid
AssigneeMercian Corporation
InventorsTadashi Fujii, Yasuhide Aritoku, Manabu Mukaihara, Takao Narita, Hitosi Agematu, Kunio Isshiki
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Abstract
A process for the production of L-pipecolic acid which comprises the step of reducing delta-1-piperideine-6-carboxylic acid by the use of pyrroline-5-carboxylate reductase. A recombinant bacterium which can be used in this production process is also provided. Thus, the present invention can provide an efficient biological process for the production of L-pipecolic acid (or 2-piperidinecarboxylic acid).
Claims11
A process for the production of L-pipecolic acid which comprises the step of reducing delta-1-piperideine-6-carboxylic acid by the use of pyrroline-5-carboxylate reductase.
A recombinant strain of Escherichia coli or a coryneform bacterium which contains a gene encoding lysine 6-aminotransferase in expressible form.
Dependencies are inferred from the claim text.