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US 2003/0077772 A1Published application
Method for formulating and immobilizing a protein matrix and a protein matrix for use in a sensor
AssigneeMedtronic MiniMed, Inc.
InventorsRajiv Shah, Bahar Reghabi, Rudolph A. Montalvo, Yanan Zhang
Life of this patent
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Abstract
A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix that has low swelling, non-leaching, high activity, and high mechanical strength properties. The method includes cross-linking and hardening the protein mixture and using a mold to form a protein into a desired shape and size.
Claims31
A method for formulating a protein comprising:
- combining a protein mixture with a cross-linking reagent;
- placing the protein mixture into a mold after combining the protein mixture with a cross-linking reagent;
- hardening the protein mixture;
- and
- removing the hardened protein mixture from the mold.
2 more elements
A sensor comprising:
- a sensor body;
- and
- an active protein disposed within the sensor body, the active protein comprising gluscose oxidase, human serum albumin, and a cross-linking reagent.
Dependencies are inferred from the claim text.