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US 2003/0077264 A1Published application
Antimicrobial blood treatment using allicin and related compounds
OwnerLaura L. Goodrichinventor
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OwnerLaura L. Goodrichinventor
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Methods and compositions prolonging the storage life and/or increasing the safety of a blood product, such as whole blood, red blood cells, white blood cells, platelets, serum and aqueous additive solutions for storage of such blood products are provided. Storage solutions of this invention comprise a composition selected from the group consisting of garlic extract, allicin, other microorganism-growth-inhibiting compounds derived from garlic, and analogs and derivatives of allicin and said other compounds, in an amount effective to inhibit growth of at least one selected microorganism which is a bacterium, virus, fungus or parasite. The storage additive solutions of this invention can increase platelet storage life by at least about 20%, preferably at least about 40%.
An aqueous additive solution for blood products comprising a composition comprising a microorganism-growth-inhibiting compound derived from garlic or analog thereof, in an amount effective to inhibit growth of at least one selected microorganism.
A method of reducing contamination of a blood product comprising:
A method of storing a blood product comprising:
A method of treating a patient in need of a blood product comprising:
A composition comprising an anticoagulant and a solution comprising a composition comprising a microorganism-growth-inhibiting compound derived from garlic or analog thereof in an amount effective to inhibit growth of at least one selected microorganism.
Dependencies are inferred from the claim text.