Method of determining and reducing the risk of bph-related urologic events
OwnerElizabeth Stoner, Daniel Z. Wang +1inventors
InventorsELIZABETH STONER, DANIEL Z. WANG, JOANNE WALDSTREICHER
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Abstract
This invention is concerned with a method of determining the risk of a urologic event, particularly an event selected from BPH-related surgery and acute urinary retention in a man by measuring the man's serum PSA level. The present invention also provides for a method of reducing the risk of the urologic event in a man determined to be at risk by the present urologic event risk-determining method by administration to the man of a compound which inhibits 5α-reductase. Also provided is a kit for determining the risk of a urologic event.
Claims25
A method for determining the risk of a urologic event in a man, comprising measuring the serum PSA of the man.
A method for reducing the risk of a urologic event in a man at risk for a urologic event by having a serum PSA level of over 1.3 ng/mL, comprising administration of an inhibitor of 5α-reductase to the man.
A method for reducing the risk of a urologic event in a man at risk for a urologic event by having a serum PSA level of over 3.3 ng/mL, comprising administration of an inhibitor of 5α-reductase to the man.
A kit for determining the risk of a urologic event in a male subject comprising a test for serum PSA measurement and a means for relating the serum PSA measurement to the risk of a urologic event.
Dependencies are inferred from the claim text.