Alpha-N-acetylgalactosaminidase from Clostridium perfringens
AssigneeThe Curators of the University of Missouri
InventorDaniel S. Smith
Life of this patent
Estimating the term…
Abstract
An isolated and purified α-N-acetyl-D-galactosaminidase from Clostridium perfringens and homologs thereof are disclosed. A method for purifying and isolating the α-N-acetylgalactosaminidase from Clostridium perfringens by removing neuramidases is disclosed. A process for using the α-N-acetylgalactosaminidase from Clostridium perfringens in altering type A blood cells to type O blood cells is disclosed. A process for altering cells expressing blood group A epitope by using α-N-acetylgalactosaminidase isolated from Clostridium perfringens in altering the cells expressing blood group A epitope to cells expressing blood group O epitope is disclosed.
Claims12
An isolated and purified α-N-acetyl-D-galactosaminidase from Clostridium perfringens and homologs thereof.
A method for removing neuramidases from α-N-acetylgalactosaminidase isolated from Clostridium perfringens.
A process for altering erythrocytes by using α-N-acetyl-D-galactosaminidase isolated from Clostridium perfringens or homologs thereof in altering erythrocytes to type O blood cells.
A recombinant α-N-acetyl-D-galactosaminidase as set forth in SEQ ID No:1 and 8-15 and functional analogs thereof.
An antibody for testing the purity of α-N-acetylgalactosaminidase isolated from Clostridium perfringens.
A process for altering cells expressing blood group A epitope by using α-N-acetylgalactosaminidase isolated from Clostridium perfringens in altering the cells expressing blood group A epitope to cells expressing blood group O epitope.
A process for altering cells expressing blood group A epitope by using α-N-acetylgalactosaminidase isolated from Clostridium perfringens in altering the cells expressing blood group A epitope to cells expressing blood group B epitope.
Dependencies are inferred from the claim text.