US 2003/0068653 A1 · Determining existence of complications in pregnancies by measuring levels of bioactive lipids

Abstract

The present invention relates generally to methods for detecting complications, or abnormal conditions occurring during pregnancy, including placental abnormalities, eclampsia, or preelcampsia. The present invention comprises the steps of obtaining a sample from a patient, assaying the specimen to determine the level of bioactive lipids and comparing levels in the sample to control values or levels in normal samples, and correlating alterations to disease. The invention includes measuring panels of bioactive lipids to screen patients for disease and to monitor the progress of disease for diagnostic or therapeutic purposes.

Claims10

Dependent claims

A method for detecting preeclampsia by measuring bioactive lipids comprising:

obtaining a sample from a pregnant patient;
assaying the sample to determine the concentration of at least one bioactive lipid in the sample, wherein the lipid is selected from the group consisting of a glycerophosphatidyl compound, a lysophospholipid and a sphingolipid;
comparing the level of bioactive lipid in the sample to a control value or a prior sample from the pregnant patient;
and
correlating the concentration in the sample to preeclampsia.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

10/267,556Filed 8 Oct 2002

Priority

1 Jun 2000

Published

10 Apr 2003

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C12Q 1/26
Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; Compositions therefor; Processes of preparing such…
C12Q 1/32
Involving oxidoreductase: involving dehydrogenase
C12Q 1/44
Involving hydrolase: involving esterase
G01N 2333/902
Enzymes; Proenzymes: oxidoreductases

Determining existence of complications in pregnancies by measuring levels of bioactive lipids

Life of this patent

Determining existence of complications in pregnancies by measuring levels of bioactive lipids

Life of this patent

Abstract

Claims10