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US 2003/0068338 A1Published application
Pharmaceutical emulsions for retroviral protease inhibitors
AssigneePharmacia & Upjohn Company
InventorsYoumin Wang, Walter Morozowich
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Abstract
The present invention provides an emulsion formulation with high oral bioavailability containing lecithin as an emulsifier and solubilizing agent to achieve a high loading of the pyranone compound of formula I. 1
Claims21
A pharmaceutical composition comprising:
- a therapeutically effective amount of the compound of formula I
- 3
- (b) an oil component selected from the group consisting of mono-, di-, tri-glyceride or a mixture thereof wherein the monoglyceride and diglyceride are mono- and di-unsaturated fatty acid esters of glycerol having sixteen to twenty-two carbon atom chain length, wherein triglyceride is a saturated fatty acid ester of glycerol having six to twelve carbon atom chain length,
- (c) an emulsifying agent consisting of lecithin, and
- (d) a liquid phase comprising one or more pharmaceutically acceptable solvents.
2 more elements
Dependencies are inferred from the claim text.