Diagnostic method for a transmissible spongiform encephalopathy or a prion disease
AssigneeRoslin Institute (Edinburgh)
InventorsMichael Clinton, Gino Miele, Jean Catherine Manson
Life of this patent
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Abstract
A method is provided for the diagnosis of a transmissible spongiform encephalopathy (TSE) or prion disease in an animal which comprises assaying a sample obtained from said animal to determine the number of hematopoietic cells of the erythroid, megakaryocyte or platelet cell lineages in the sample or an expression product thereof.
Claims14
A method of diagnosis for the presence of a transmissible spongiform encephalopathy in an animal, comprising assaying a sample obtained from the animal to determine the relative number of hematopoietic cells of the erythroid, megakaryocyte or platelet lineages in the sample.
A method of diagnosis for the presence of a transmissible spongiform encephalopathy in an animal, comprising assaying a sample obtained from the animal to determine the relative amount in the sample of an expression product of a hematopoietic cell of erythroid, megakaryocyte or platelet lineages.
A kit for diagnosis for the presence of a transmissible spongiform encephalopathy in an animal, where the kit comprises an antibody to a cell of the hematopoietic erythroid, megakaryocyte or platelet lineages.
A kit for the diagnosis for the presence of a transmissible spongiform encephalopathy in an animal, where the kit comprises an antibody to an expression product of a cell of the hematopoietic erythroid, megakaryocyte or platelet lineages.
A kit as claimed in 13, in which the expression product of a cell of the hematopoietic erythroid, megakaryocyte or platelet lineages to which the antibody binds is Erythroid Differentiation Related Factor.
Dependencies are inferred from the claim text.