Mesoporous compositions for use in drug delivery
AssigneeBoard of Regents, The University of Texas System
InventorsYing Ma, Kenneth J. Balkus JR.
Life of this patent
Estimating the term…
Abstract
The present invention encompasses novel mesoporous compositions comprising vitamin E and alumina, and methods for their synthesis. The mesoporous compositions of the present invention have applications as drug-delivery vehicles.
Claims37
A method for preparing a mesoporous composition, comprising the steps of:
- (A) dissolving a first compound possessing amphipathic properties together with an alumina source in a first solvent to form a mixture;
- (B) stirring the mixture of step (A);
- (C) adding a second solvent to the stirred mixture of step (B) accompanied by further stirring;
- (D) aging the further stirred mixture of step (C) to form a product;
- (E) evaporating the product of step (D);
- and,
- (F) washing, filtering and drying the evaporated product of step (E).
A mixture for the preparation of a mesoporous composition comprising vitamin E TPGS, sec-butanol, water and an alumina source.
A mixture for the preparation of a mesoporous composition comprising vitamin E TPGS, ethanol, water and an alumina source.
A mesoporous composition suitable for use in a drug delivery system prepared from a mixture comprising alumina, vitamin E TPGS, water and sec-butanol.
Dependencies are inferred from the claim text.