Expression of recombinant human acetylcholinesterase in transgenic plants
OwnerTsafrir S. Mor, Hermona Soreq +2inventors
InventorsTsafrir S. Mor, Hermona Soreq, Charles J. Arntzen, Hugh S. Mason
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OwnerTsafrir S. Mor, Hermona Soreq +2inventors
InventorsTsafrir S. Mor, Hermona Soreq, Charles J. Arntzen, Hugh S. Mason
Estimating the term…
Briefly stated, the invention includes a method of making a transgenic plant that is capable of expressing a physiologically active human acetylcholinesterase, comprising the steps of introducing into at least one plant cell a polynucleotide that encodes a human acetylcholinesterase, and regenerating from the plant cell a transgenic plant that is capable of expressing a physiologically active human acetylcholinesterase in at least one tissue type of the transgenic plant. Another embodiment of the invention includes a method of making a physiologically active human acetylcholinesterase, comprising the steps of introducing into at least one plant cell a polynucleotide that encodes a human acetylcholinesterase, regenerating from the plant cell a transgenic plant that is capable of expressing a physiologically active human acetylcholinesterase in at least one tissue type of the transgenic plant, and isolating or purifying from the transgenic plant or a part thereof a physiologically active human acetylcholinesterase.
One or more plant cells comprising a polynucleotide that encodes a human acetylcholinesterase.
A method of making a transgenic plant that is capable of expressing a physiologically active human acetylcholinesterase, comprising the steps of:
A method of making a physiologically active human acetylcholinesterase, comprising the steps of:
A method of treating a victim of acetylcholinesterase poisoning, comprising the step of administering a therapeutic amount of a physiologically active human acetylcholinesterase expressed in plant tissue.
An isolated polynucleotide comprising a nucleic acid molecule including a sequence selected from the group consisting of:
A synthetic polynucleotide comprising a nucleic acid molecule that encodes a human acetylcholinesterase.
Dependencies are inferred from the claim text.