New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them

As a new industrial product, a compound of general formula MX

• 46
• wherein R represents a lower alkyl.

A method of treatment of diseases related with topoisomerase I and/or topoisomerase II disorders, and especially cancer, viral and parasitic diseases, comprising the administration of a therapeutically efficient dose of a camptothecin analog, said camptothecin analog being characterized in that it features a β-hydroxy lactone instead of the α-hydroxy lactone of natural camptothecin.