Cloning and recombinant expression of mammalian group XII secreted phospholipase A2
OwnerMichel Lazdunski, Gerard Lambeau +1inventors
InventorsMichel Lazdunski, Gerard Lambeau, Emmanuel Valentin
Life of this patent
Estimating the term…
Abstract
This invention concerns DNA and peptide sequences encoding a novel mammalian secreted group XII phospholipase A2 wherein said enzyme contains a potential Ca2+ binding segment GCGSP and more particularly, a novel human group XII phospholipase A2. The invention also concerns the use of this enzyme in methods for screening various chemical compounds.
Claims19
1) A mammalian secreted group XII sPLA2 containing a potential Ca2+ binding segment GCGSP.
4) A nucleic acid molecule comprising an encoding nucleic sequence for a mammalian secreted group XII sPLA2 or for a fragment of a mammalian secreted group XII sPLA2 having SEQ ID No2.
Dependencies are inferred from the claim text.