Two-component anti-emetic composition
OwnerAnthony Jannettainventor
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Abstract
The invention relates to an anti-emetic composition containing dexamethasone (DEX) and metoclopramide (MTC). In a particular embodiment, a composition containing DEX:MTC in a relative weight ratio of about 1 to less than 1.25 is found to be effective in providing relief from the discomfort caused by symptoms of both vomiting and nausea in all patients receiving the composition. Alternatively, an effective suppository composition may contain DEX:MTC in a relative weight ratio of about 1:1-12.5. Other effective compositions and methods of their use are also disclosed.
Claims29
An anti-emetic composition to be administered to a patient in need thereof, the composition comprising the combination of dexamethasone (DEX) and metoclopramide (MTC), wherein the weight ratio of DEX to MTC is about 1 to less than about 1.25.
A method of providing an anti-emetic relief to a patient in need thereof, said method comprising administering an effective amount of an oral pharmaceutical composition comprising the combination of dexamethasone (DEX) and metoclopramide (MTC), wherein the weight ratio of DEX to MTC is about 1 to about 1-12.5.
An anti-emetic suppository to be administered to a patient in need thereof, the composition comprising the combination of dexamethasone (DEX) and metoclopramide (MTC), wherein the weight ratio of DEX to MTC is about 1 to about 1-12.5.
An anti-emetic composition to be administered to a patient in need thereof, the composition comprising the combination of a corticosteroid and an N-substituted benzamide, wherein the weight ratio of the corticosteroid to the N-substituted benzamide, is about 1 to less than about 1.25.
Dependencies are inferred from the claim text.