Corynebacterium glutamicum strain with enhanced secretion activity
AssigneeDegussa AG
InventorsStephan Berens, Jorn Kalinowski, Alfred Puhler
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Abstract
The present invention refers to a Corynebacterium glutamicum bacterial strain which new isolated and identified secD and/or secF gene(s) is/are genetically modified in a way that secretion of the bacterial strain is enhanced, the protein- and polynucleotide sequences of these genes, a plasmid containing at least one of these genes and the use of such a bacterial strain for production of a desired substance or in a reporter system.
Claims19
Genetically modified bacterial strain Corynebacterium glutamicum, characterized in that genetical modification concerns at least one of the genes secD and secF of this strain.
Protein with the sequence SEQ ID NO. 3 (SecD) or SEQ ID NO. 4 (SecF) or respective homologous protein or functional mutant or fragment thereof.
Plasmid, containing at least one of the sequences SEQ ID NO. 1, SEQ ID NO. 2, or fragments or mutants thereof.
Dependencies are inferred from the claim text.