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AssigneeAnadys Pharmaceuticals, Inc.
InventorsYueh-Tyng Chien, Jason A. Thresher, C. Richard Wobbe, Judith M. Healy
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The present invention provides an isolated Staphylococcal GTPase obg gene and a Staphylococcal GTP-binding protein encoded thereby. A recombinant expression vector and an engineered host cell are also provided that include a polynucleotide encoding a Staphylococcal GTP-binding protein. The present invention further relates to a method of producing Staphylococcal GTP-binding protein and a method for high throughput screening to identify potential antimicrobial compounds useful against Staphylococcal bacterial strains.
An isolated polynucleotide that encodes a Staphylococcal GTP-binding protein.
An isolated and purified polypeptide comprising a Staphylococcal GTP-binding protein.
A recombinant expression vector comprising a polynucleotide that encodes a Staphylococcal GTP-binding protein.
An engineered host cell for use in producing Staphylococcal GTP-binding protein, wherein said engineered host cell comprises an isolated polynucleotide that encodes a Staphylococcal GTP-binding protein.
A method of producing Staphylococcal GTP-binding protein comprising the steps of:
A method for high throughput screening to identify potential antimicrobial compounds useful against Staphylococcal bacterial strains, said method comprising the steps of:
Dependencies are inferred from the claim text.