Reversal of viral-induced systemic shock and respiratory distress by blockade of the lymphotoxin beta pathway
OwnerJeffrey Browning, Maryann Puglielli +1inventors
InventorsJeffrey Browning, Maryann Puglielli, Rafi Ahmed
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Abstract
This invention provides methods of inducing an antiviral response in an individual comprising administering to the individual an effective amount of a LT-B blocking agent and a pharmaceutically acceptable carrier. In particular this invention provides methods for treating viral-induced systemic shock and respiratory distress.
Claims8
A method of inducing an antiviral response in an individual comprising administering to the individual an effective amount of an agent which blocks the binding of lymphotoxin-β to its receptor, and a pharmaceutically acceptable carrier.
A method of inducing an antiviral response in an individual comprising administering to the individual an effective amount of an agent which blocks the lymphotoxin-β-receptor and/or HVEM signaling pathway.
Dependencies are inferred from the claim text.