Novel method for treating gut disorders using polyanionic polyglycosides
AssigneeNorton Healthcare Limited
InventorStephen Dealler
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Abstract
The present invention relates to a method for combatting gut disorders such as Crohn's disease and ulcerative colitis using polyanionic polyglycosides (eg polysulphonated polyglycosides).
Claims35
A method for combatting a gut disorder in a subject, said method comprising:
- administering to the subject an effective amount of a polyglycoside (or a mixture of polyglycosides) or a salt thereof (eg a calcium, sodium, magnesium, potassium or ammonium salt thereof),
- wherein the polyglycoside comprises a chain of glycosidic residues substituted regularly or irregularly with an anionic substituent.
An orally administrable, sustained release formulation comprising a polyglycoside (or a mixture of polyglycosides) or a salt thereof, wherein the polyglycoside comprises a chain of glycosidic residues substituted regularly or irregularly with an anionic substituent.
An orally administrable formulation in the form of an enterically coated unit comprising a polyglycoside (or a mixture of polyglycosides) or a salt thereof, wherein the polyglycoside comprises a chain of glycosidic residues substituted regularly or irregularly with an anionic substituent.
An orally administrable formulation comprising a polyglycoside or a salt thereof, together with one or more carriers or excipients, wherein the polyglycoside comprises a chain of glycosidic residues substituted regularly or irregularly with an anionic substituent and wherein the polyglycoside is capable of entering the intercellular fluid and is present in an amount sufficient to prevent or inhibit a gut disorder.
Dependencies are inferred from the claim text.