Composition and method for delivery of biologically-active factors
OwnerLawrence Tamarkin, Giulio F. Paciottiinventors
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OwnerLawrence Tamarkin, Giulio F. Paciottiinventors
Estimating the term…
In accordance with the present invention, a composition and method is provided that allows for the administration of a biologically-active factors to a human or animal. The present invention can be used to treat a disease with a biologically-active factor or combination of biologically-active factors, or can be used to safely vaccinate a human or animal against a biologically-active factor. It can also be used as a method for the delivery of biologically-active factors for the treatment of disease. Additionally, the present invention also includes a method of targeted drug delivery for the treatment of disease through the administration of custom complexes containing of one or more biologically active factors bound to a colloidal metal where at least one of the biologically-active factors is capable of binding a high affinity receptor on a cell surface.
A composition comprising an admixture of a colloidal metal and a biologically-active factor.
A composition capable of targeting a particular tissue comprising a colloidal metal associated with a target molecule and a biologically-active factor.
A method of administering a biologically-active factor to a human or animal comprising the step of administering to the human or animal, an effective amount of a composition comprising an admixture of a colloidal metal and the biologically-active factor.
A method of vaccinating a human or animal against disease comprising the step of administering to the human or animal a composition comprising an immunologically effective amount of an admixture of a colloidal metal and a biologically-active factor.
A method of treating a human or animal with a cancer or immune disease comprising the step of administering to the human or animal with the cancer or immune disease a therapeutically effective amount of a composition comprising an admixture of a colloidal metal and a toxic biologically-active factor.
A method for the delivery of one or more biologically-active factors comprising administering to a human or animal a composition comprising one or more biologically-active factors bound to a colloidal metal.
A method for the targeted delivery of one or more biologically-active factors comprising administering to a human or animal a composition comprising one or more biologically-active factors wherein at least one of the biologically-active factors is a target molecule capable of binding a receptor on a cell membrane.
A method of treating a human or animal with cancer or an immune disease comprising administering to a human or animal a composition comprising one or more biologically-active factors wherein at least one of the biologically-active factors is a target molecule capable of binding high affinity receptor on a cell membrane.
The method of claim 30 wherein the target molecule is selected from the group consisting of Interleukin-1 (“IL-1”), Interleukin-2 (“IL-2”), Interleukin-3 (“IL-3”), Interleukin-4 (“IL-4”), Interleukin-5 (“IL-5”), Interleukin-6 (“IL-6”), Interleukin-7 (“IL-7”), Interleukin-8 (“IL-8”), Interleukin-10 (“IL-10”), Interleukin-11 (“IL-11”), Interleukin-12 (“IL-12”), Interleukin-13 (“IL-13”), Type I Interferon, Type II Interferon, Tumor Necrosis Factor (“TNFα”), Transforming Growth Factor-β (“TGFβ”), vascular epithelial growth factor (“VEGF”), receptor proteins, glucose, glycogen, phosphoipids, and monoclonal and/or polyclonal antibodies, and transforming growth factor alpha (“TGFα”).
Dependencies are inferred from the claim text.