Loading patent…
AssigneePhiladelphia Health and Education Corporation
InventorsREINER J. W. CLASS, CHRISTOPHER M. HAND
Estimating the term…
The invention includes antibiotic pharmaceutical compositions comprising eukaryotic histone H1 protein and methods of using eukaryotic histone H1 protein to kill or to inhibit the growth of microorganisms, including, but not limited to, human pathogenic bacteria. The invention further includes a eukaryotic histone H1-containing animal feed and methods of improving growth of an animal by supplying the feed to the animal. The invention still further includes a kit comprising a eukaryotic histone H1-containing antibiotic pharmaceutical composition and an instructional material which describes the use of the composition. In addition, the invention includes a vaccine comprising a eukaryotic histone H1 protein and a method of vaccinating an animal using the vaccine.
A method of inducing death of a microorganism, said method comprising contacting said microorganism with a composition comprising a substantially purified eukaryotic histone H1 protein, whereby death of said microorganism is induced.
The method of claim 4, wherein said pathogen is a bacterium.
A method of inhibiting growth of a microorganism, said method comprising contacting said microorganism with a composition comprising a substantially purified eukaryotic histone H1 protein.
An antimicrobial pharmaceutical composition comprising a substantially purified eukaryotic histone H1 protein and a pharmaceutically acceptable carrier.
A method of treating a microbial infection in an animal, said method comprising administering an antimicrobial composition comprising a substantially purified eukaryotic histone H1 protein to said animal.
A method of inhibiting microbial growth at a site, said method comprising providing an antimicrobial composition comprising a eukaryotic histone H1 protein to said site.
A supplemented animal feed comprising an animal feed supplemented with an antimicrobial composition comprising a substantially purified eukaryotic histone H1 protein.
A method of preparing an animal vaccine, said method comprising adding a eukaryotic histone H1 protein to a preparation of a microorganism, whereby said microorganism is killed, said preparation of said killed microorganism comprising said vaccine.
A method of vaccinating an animal, said method comprising administering to said animal a composition comprising an attenuated or killed form of a microorganism and a substantially purified eukaryotic histone H1 protein.
Dependencies are inferred from the claim text.