Method for the prevention or treatment of a motoneuron disease
AssigneeAventis Pharma S. A.
InventorsMichel Dib, Jean-Marie Stutzmann
Life of this patent
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Abstract
The present invention relates to a method for the prevention or treatment of a motoneuron disease with a combination of an ergoline chosen from nicergoline and lumilysergol and of riluzole or one of its pharmaceutically acceptable salts.
Claims11
A method for the prevention or treatment of a motoneuron disease comprising administering to a patient in need of such treatment an effective amount of a riluzole compound selected from riluzole and the pharmaceutically acceptable salts thereof and an effective amount of an ergoline compound selected from the group consisting of nicergoline and lumilysergol.
A pharmaceutical composition comprising a synergistically effective combination of an effective amount of a riluzole compound selected from riluzole and the pharmaceutically acceptable salts thereof and an effective amount of nicergoline or lumilysergol.
A pharmaceutical kit for the prevention or treatment of a motoneuron disease, said kit comprising a plurality of separate containers, at least one of said containers containing a riluzole compound selected from riluzole and the pharmaceutically acceptable salts thereof and at least another of said containers containing nicergoline or lumilysergol.
A method for the prevention or treatment of a motoneuron disease comprising contacting motoneurons in vitro with an effective amount of a riluzole compound selected from riluzole and the pharmaceutically acceptable salts thereof and an effective amount of an ergoline compound selected from the group consisting of nicergoline and lumilysergol.
Dependencies are inferred from the claim text.