Apparatus for the internal depressurization of plastic containers thermoformed by means of blowing and intended for sterile filling, characterized in that the said depressurization step is performed by means of the secondary suction circuit of a Venturi meter or ejector (15), the primary circuit of which is passed through by compressed air at pressure values regulated by a proportional valve (19) controlled by an electronic control unit (10) which detects the internal pressure or vacuum of the containers by means of a transducer (9) and which is programmed by means of a suitable programming apparatus (11) and which, upon reaching of the predetermined vacuum inside the containers, activates means (Z) for closing the end portion of the said thermoformed containers.