Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders

Use of compounds of the formula (I)

• T—Q (I),
• in which
• Q represents a radical of the formulae
• 77
• in which
• R1 represents alkyl having 1 to 4 carbon atoms which is optionally mono- to trisubstituted by halogen or hydroxyl, alkenyl having 2 to 4 carbon atoms, cycloalkyl having 3 to 6 carbon atoms which is optionally substituted by 1 or 2 fluorine atoms, bicyclo[1.1.1 ]pent-1-yl, 1,1-dimethylpropargyl, 3-oxetanyl, methoxy, amino, methylamino, dimethylamino, phenyl which is optionally mono- or disubstituted by halogen, amino or hydroxyl, isoxazolyl, thiadiazolyl,
• R2 represents hydroxyl, alkoxy having 1 to 4 carbon atoms which is optionally substituted by hydroxyl, methoxy, amino, dimethylamino or ethoxycarbonyl, benzyloxy, allyloxy, propargyloxy or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyloxy, acetoxymethyloxy, pivaloyloxymethyloxy, 5-indanyloxy, phthalidinyloxy, 3-acetoxy-2-oxo-butyloxy, nitromethyl or dialkoxycarbonylmethyl having 1 to 2 carbon atoms in each alkyl moiety,
• R3 represents hydrogen, amino, hydroxyl, methyl or halogen,
• R9 represents hydrogen or optionally methoxy-, hydroxyl- or halogen-substituted alkyl having 1 to 3 carbon atoms,
• R11 represents hydrogen, CH3 or CH2F,
• A represents N or C—R7 in which
• R7 represents hydrogen, halogen, CF3, OCH3, OCHF2, CH3, CN, CH═CH2 or C—CH or else together with R1 may form a bridge of the structure —*O—CH2—CH—CH3, —*S—CH2—CH2—, —*S—CH2—CH—CH3, —*CH2—CH2—CH—CH3 or —*O—CH2—N—R8 where the atom marked with is attached to the carbon atom of A and in which
• R8 represents hydrogen, methyl or formyl,
• B represents N, C—H, C—F, C—Cl, C—NO2, C—NH2,
• D represents N or C—R10 in which
• R10 represents hydrogen, halogen, CF3, OCH3, OCHF2 or CH3 or else together with R9 may form a bridge of the structure —O—CH2—, —*NH—CH2—, —N(CH3)—CH2—, —*N(C2H5)—CH2—, —N(c—C3H5)—CH2— or —*S—CH2— where the atom marked with * is attached to the carbon atom of D,
• Y represents hydrogen or together with R2 may form a bridge of the structure —*S—NH— where the atom marked with * represents Y, and
• T represents a radical of the formula
• 78
• in which
• R4 represents H, CH3, C2H5, optionally amino-substituted acyl having 1 to 5 carbon atoms, alkoxycarbonyl, aminocarbonyl, alkylthio-thiocarbonyl and dialkoxyphosphoryl having 1 to 4 carbon atoms in the alkyl moiety,
• R5 represents H, CH3, C2H5 and
• R6 represents H, CH3,
• and their pharmaceutically useful hydrates and acid addition salts and the alkali metal, alkaline earth metal, silver and guanidinium salts of the parent carboxylic acids for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders.