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US 2001/0036674 A1Published application
Chips having elevated sample surfaces
AssigneeZyomyx, Inc.
InventorsPierre F. Indermuhle, Frank G. Zaugg, Peter Wagner, Steffen Nock
Life of this patent
Estimating the term…
Abstract
A chip is disclosed. The chip includes a base including a non-sample surface and at least one structure includes a pillar. Each structure includes a sample surface that is elevated with respect to the non-sample surface and each structure may be adapted to receive a sample.
Claims63
A chip comprising:
- a) a base including a non-sample surface;
- and
- b) at least one structure, each structure comprising a pillar and a sample surface that is elevated with respect to the non-sample surface and is adapted to receive a sample from a dispenser.
An assembly adapted to process fluids, the assembly comprising:
- a) a dispenser comprising a body and at least one fluid channel defined in the body, each fluid channel being adapted to dispense a fluid on one or more of the sample surfaces;
- and
- b) a chip comprising (i) a base including a non-sample surface, and (ii) at least one structure, each structure comprising a pillar and a sample surface that is elevated with respect to the non-sample surface and is adapted to receive the fluid from the dispenser.
A method of processing fluids, the method comprising:
- a) supplying a fluid in a fluid channel in a dispenser;
- and
- b) dispensing the fluid on one or more structures on a base of a chip, wherein each structure comprises a pillar and includes a sample surface that is elevated with respect to the non-sample surface.
A method of processing fluids, the method comprising:
- a) supplying a plurality of liquids to respective fluid channels in a dispenser, wherein each of the fluid channels includes a passive valve and wherein the flow of each liquid in each fluid channel stops at the passive valve;
- b) aligning sample surfaces of a plurality of structures with the plurality of fluid channels, wherein each structure comprises a pillar;
- and
- c) contacting the sample surfaces and the liquids in the fluid channels while the sample surfaces are in, or are positioned at ends of, the fluid channels.
1 more element
A chip comprising:
- a) a base including a non-sample surface;
- and
- b) a plurality of structures in an array on the base, each structure comprising a pillar and a sample surface that is elevated with respect to the non-sample surface and is adapted to receive a sample from a dispenser to be processed or analyzed while the sample is on the sample surface.
An assembly comprising:
- a) a chip comprising:
- i) a base including a non-sample surface;
- and ii) a plurality of structures in an array on the base, each structure comprising a pillar and a sample surface that is elevated with respect to the non-sample surface and is adapted to receive a sample to be processed or analyzed while the sample is on the sample surface;
- and
- b) a dispenser including a plurality of fluid channels, each fluid channel including a passive valve.
2 more elements
Dependencies are inferred from the claim text.