Use of amino-isoxazolidone compounds for improvement of implicit memory
AssigneeG.D. Searle & Co.
InventorsRobert L. Herting, Barbara L. Schwartz, Stephen I. Deutsch
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Abstract
A class of amino-isoxazolidone compounds is described for use to improve implicit memory in patients susceptible to or afflicted with Alzheimer's Disease. Preferred compounds of this class are D-cycloserine and its prodrugs.
Claims11
A method to improve implicit memory in a subject susceptible to or suffering from impairment of implicit memory, said method comprising administering a therapeutically-effective amount of a glycine B partial agonist to said subject.
A therapeutic method for treating impairment of implicit memory in a subject susceptible to or afflicted with Alzheimer's Disease when therapy is indicated, comprising administering to said subject a therapeutically-effective amount of D-4-amino-3-isoxazolidone or a pharmaceutically-acceptable salt thereof.
Dependencies are inferred from the claim text.